Open Stage Seminar Oct. 11 (Wed.) ,2017 13:00-14:00

Special Seminar 

Nanobiodevices and AI for Super Smart Society and Healthy and Longevity Society

Yoshinobu Baba

Department of Biomolecular Engineering, Department of Advanced Medical Science, ImPACT Research Center for Advanced Nanobiodevices, Nagoya University

I will describe the development of nanobiodevices and AI for super smart society (society 5.0) and healthy and longevity society.  Immuno-wall devices realized the fast and low invasive “from blood to analysis” type biomarker detection of cancer with fM detection sensitivity within 2 min.  Additionally, nanopillar devices give us ultrafast electophoretic separation of DNA and microRNA within 60 µs and nanopillar-nanopore integrated nanobiodevice enables us ultarafast single molecular DNA sequencing.  Nanowire devices coupled with super-resolution optical microscopy are extremely useful to analyze exosomes from cancer cells and exosomal microRNA analysis.  Nanowire-nanopore devices combined with machine learning technique enable us to develop mobile sensors for PM2.5, bacteria, and virus in the environment. Quantum dots are applied to develop quantum-biodevices for single cancer cell diagnosis, single molecular epigenetic analysis, quantum switching in vivo imaging for iPS cell (induced pluripotent stem cells) based regenerative medicine, and theranostic devices for cancer diagnosis/therapy.  

In vivo imaging of transplanted stem cells by quantum nano materials for regenerative medicine

Hiroshi Yukawa

Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University

The diagnosis of the dynamics, accumulation and engraftment of transplanted stem cells in vivo are essential for ensuring the safety and the maximum therapeutic effect of regenerative medicine. However, in vivo imaging modalities for detecting transplanted stem cells are not sufficient at present. In this seminar, I would like to introduce the latest data about the stem cell labeling and in vivo imaging of transplanted stem cells using quantum nano materials such as quantum dots (QDs) and magnetic nano particles (TMADM) which have excellent fluorescence and magnetic properties.